Publications

Title Yearsort ascending
Rational design of glycomimetic compounds targeting the Saccharomyces cerevisae transglycosylase Gas2. Chemical Biology & Drug Design, 2016
Glycomimetics Targeting Glycosyltransferases: Synthetic, Computational and Structural Studies of Less-polar Conjugates. 2016
Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine causing Parasite Death. 2016
Mucin Architecture behind the Immune Response: Design, Evaluation and Conformational Analysis of an Antitumor Vaccine Derived from an Unnatural MUC1 Fragment. 2016
Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1). 2016
Structural and Functional Analysis of Yeast Crh1 and Crh2 Transglycosylases. 2015
X-ray Structures decipher the Non-equivalence of Serine and Threonine O-glycosylation points: Implications for the Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody. 2015
Detection of Tumor-Associated Glycopeptides by Lectins: the Peptide Context Modulates Carbohydrate Recognition. 2015
Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation. 2015
Pharmacophore-based virtual screening to discover new active compounds for human choline kinase α1. 2015
A hydrogen bond network in the active site of Anabaena Ferredoxin-NADP+ reductase modulates its catalytic efficiency. 2014
Discovery of a new binding site on human choline kinase α1: design, synthesis, crystallographic studies and biological evaluation of asymmetrical bispyridinium derivatives. 2014
Choline kinase active site provides features for designing versatile inhibitors. 2014
Combined structural snapshots and metadynamics reveal a substrate-guided front-face reaction for polypeptide GalNAc-transferase T2 . 2014
Serine versus Threonine Glycosylation with a-O-GalNAc: Implications for the molecular recognition by lectins. 2014
The Mechanism of Allosteric Coupling in Choline Kinase α1 Revealed by the Action of a Rationally Designed Inhibitor. 2013
Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal target 2013
Genetic and structural validation of Aspergillus fumigatus N-acetylphosphoglucosamine mutase as an antifungal target 2013
rystal structure of the FAD-containing ferredoxin-NADP+ reductase from the plant pathogen Xanthomonas axonopodis pv. citri. 2013
Characterization of the cDNA and in vitro expression of the ram seminal plasma protein RSVP 14 2013

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