Publications

Title Yearsort ascending
The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements 2017
Streptococcus pneumoniae TIGR4 Flavodoxin: Structural and Biophysical Characterization of a Novel Drug Target. 2016
Rational design of glycomimetic compounds targeting the Saccharomyces cerevisae transglycosylase Gas2. Chemical Biology & Drug Design, 2016
Glycomimetics Targeting Glycosyltransferases: Synthetic, Computational and Structural Studies of Less-polar Conjugates. 2016
Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine causing Parasite Death. 2016
Mucin Architecture behind the Immune Response: Design, Evaluation and Conformational Analysis of an Antitumor Vaccine Derived from an Unnatural MUC1 Fragment. 2016
Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1). 2016
Design of alpha-S-neoglycopeptides derived from MUC1 with a flexible and solvent exposed sugar moiety. 2016
Recent structural and mechanistic insights into protein O-GalNAcylation. 2016
Kinetic and functional properties of human mitochondrial phosphoenolpyruvate carboxykinase. Biochemistry and Biophysics Reports 2016
­A proactive role of water molecules in acceptor recognition by Protein-O-fucosyltransferase 2. 2016
Design of alpha-S-neoglycopeptides derived from MUC1 with a flexible and solvent exposed sugar moiety. 2016
The closed conformation of the LDL receptor is destabilized by the low Ca++ concentration but favored by the high Mg++ concentration in the endosome. 2016
A trapped covalent intermediate of a glycoside hydrolase on the pathway to transglycosylation. Insights from experiments and QM/MM simulations. 2016
Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation. 2015
Pharmacophore-based virtual screening to discover new active compounds for human choline kinase α1. 2015
Structural and Functional Analysis of Yeast Crh1 and Crh2 Transglycosylases. 2015
X-ray Structures decipher the Non-equivalence of Serine and Threonine O-glycosylation points: Implications for the Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody. 2015
Detection of Tumor-Associated Glycopeptides by Lectins: the Peptide Context Modulates Carbohydrate Recognition. 2015
Combined structural snapshots and metadynamics reveal a substrate-guided front-face reaction for polypeptide GalNAc-transferase T2 . 2014

Pages