Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets

H. Ohtaka, S. Muzammil, A. Schön, A. Velazquez-Campoy, S. Vega, E. Freire. Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets. International Journal of Biochemistry and Cell Biology. 2004 36:1787-1799