Design, synthesis, and efficacy testing of nitroethylene- and 7-nitrobenzoxadiazol-based flavodoxin inhibitors against Helicobacter pylori drug-resistant clinical strains and in Helicobacter pylori-infected mice

S. Salillas, M. Alias, V. Michel, A. Mahia, A. Lucia, L. Rodrigues, J. Bueno, J.J. Galano-Frutos, H. De Reuse, A. Velazquez-Campoy, J.A. Carrodeguas, C. Sostres, J. Castillo, J.A. Ainsa, M.D. Diaz-de-Villegas, A. Lanas, E. Touati, J. Sancho. Design, synthesis, and efficacy testing of nitroethylene- and 7-nitrobenzoxadiazol-based flavodoxin inhibitors against Helicobacter pylori drug-resistant clinical strains and in Helicobacter pylori-infected mice. Journal of Medicinal Chemistry, 2019 62:6102-6115