Asymmetric organocatalysis in total synthesis - a trial by fire

Eugenia Marqués-López, Raquel P. Herrera, Mathias Christmann. Asymmetric organocatalysis in total synthesis - a trial by fire. Nat. Prod. Rep.. 2010, Vol. 27/2010, p. 1138-2010.

This review covers the most recent applications of organocatalysis in the synthesis of natural products and non-natural biologically active molecules. Our aim is to showcase how organocatalytic reactions have overcome some of their teething problems and how they frequently offer very practical solutions to long-standing synthetic challenges. 161 references are cited