Repositioning Tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity

R. Sant’Anna, P. Gallego, L. Robinson, A. Pereira, Ne. Ferreira, F. Pinheiro, S. Esperante, I. Pallares, O. Huerta, R. Almeida, N. Reixach, R. Insa, A. Velazquez-Campoy, D. Reverter, N. Reig, S. Ventura. Repositioning Tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity. Nature Communications. 2016 7:10787