publicaciones

Título Añoorden ascendente
Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts. 2018
Structural basis for arginine glycosylation of host substrates by bacterial effector proteins. 2018
Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition. 2018
Inhibitors against Fungal Cell Wall-remodelling Enzymes. ChemMedchem, 2018
Evidence for substrate-assisted catalysis in N-acetylphosphoglucosamine mutase. 2018
Site-Specific O-Glycosylation of Low-Density Lipoprotein Related Receptors Enhance Ligand Interactions. 2018
Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions. 2018
Luteolin can directly inhibit ppGalNAc-Ts and selectively reduce mucin-type O-glycosylation on amyloid precursor protein. 2017
The interdomain flexible linker of the polypeptide GalNAc transferases (GalNAc-Ts) dictates their long-range glycosylation preferences. 2017
NleB/SseK effectors from Citrobacter rodentium, Escherichia coli, and Salmonella enterica display distinct differences in host substrate specificity. 2017
The use of fluoroproline in MUC1 antigen enables efficient detection of antibodies in patients with prostate cancer. 2017
The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements 2017
Choline Kinase Inhibition and Docking Studies of a Series of 6-(benzylthio)-9H-purin-9-yl-pyridinium derivatives. 2017
Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1). 2016
Design of alpha-S-neoglycopeptides derived from MUC1 with a flexible and solvent exposed sugar moiety. 2016
Recent structural and mechanistic insights into protein O-GalNAcylation. 2016
Kinetic and functional properties of human mitochondrial phosphoenolpyruvate carboxykinase. Biochemistry and Biophysics Reports 2016
­A proactive role of water molecules in acceptor recognition by Protein-O-fucosyltransferase 2. 2016
Design of alpha-S-neoglycopeptides derived from MUC1 with a flexible and solvent exposed sugar moiety. 2016
The closed conformation of the LDL receptor is destabilized by the low Ca++ concentration but favored by the high Mg++ concentration in the endosome. 2016

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