Publications

Title Yearsort descending
New measuring method in isothermal titration calorimetry based on a proportional-integral controlled system 1998
Determination of the rigorous transfer function of an isothermal titration microcalorimeter with Peltier compensation 1999
Development of an isothermal titration calorimetric system with digital control and dynamic power Peltier compensation. I. Description and basic performance 2000
Development of an isothermal titration calorimetric system with digital control and dynamic power Peltier compensation. II. Characterization and operation mode. Myoglobin adsorption onto polymeric latex particles 2000
HIV-1 protease inbitors: Enthalpic versus entropic optimization of the binding affinity 2000
Thermodynamic basis of resistance to HIV-1 protease inhibition: Calorimetric analysis of the V82F/I84V active site resistant mutant 2000
Thermodynamic dissection of the binding energetics of KNI-272, a potent HIV-1 protease inhibitor 2000
The use of isothermal titration calorimetry in drug design: Applications to high affinity binding and protonation/deprotonation coupling 2001
The application of thermodynamic methods in drug design 2001
Incorporating target heterogeneity in drug design 2001
The binding energetics of first and second generation HIV-1 protease inhibitors: Implications for drug design 2001
Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes 2001
Amplification of the effects of drug-resistance mutations by background polymorphisms in HIV-1 protease from African subtypes 2002
Overcoming drug resistance in HIV-1 chemotherapy: The binding thermodynamics of amprenavir and TMC-126 to wild-type and drug-resistant mutants of the HIV-1 protease 2002
Isothermal titration calorimetry: Measuring intermolecular interactions 2003
Structural and thermodynamic basis of resistance to HIV-1 protease inhibition: Implications for inhibitor design 2003
Protease inhibition of African subtypes of HIV-1 2003
Identification of novel inhibitors of the SARS associated coronavirus main protease 3CLpro 2004
Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets 2004
Characterization of protein-protein interactions by isothermal titration calorimetry 2004

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