Publications

Title Yearsort descending
Design, Synthesis, and Evaluation of Inhibitors of Trypanosomal and Leishmanial Dihydrofolate Reductase 1999
Characterization and regulation of Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase. 2000
Novel inhibitors of Leishmanial dihydrofolate reductase. 2001
Synthesis and testing of 5-benzyl-2,4-diaminopyrimidines as potential inhibitors of leishmanial and trypanosomal dihydrofolate reductase. 2002
Kinetic properties and inhibition of Trypanosoma cruzi 3-hydroxy-3-methylglutaryl CoA reductase. 2002
Cofactor processing in galactose oxidase. 2003
Structural and kinetic studies of a series of mutants of galactose oxidase identified by directed evolution. 2004
Mitochondrial localization of the mevalonate pathway enzyme 3-Hydroxy-3-methyl-glutaryl-CoA reductase in the Trypanosomatidae. 2004
Cofactor processing galactose oxidase 2004
Inhibition of dimethylarginine dimethylaminohydrolase (DDAH) and arginine deiminase (ADI) by pentafluorophenyl (PFP) sulfonates. 2005
Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis. 2007
Glucose-6-phosphate as a probe for the glucosamine-6-phosphate N-acetyltransferase Michaelis complex. 2007
Structure of Saccharomyces cerevisiae chitinase 1 and screening-based discovery of potent inhibitors. 2007
Structural insights into mechanism and specificity of O-GlcNAc transferase. 2008
Molecular mechanisms of O-GlcNAcylation. 2008
Structural and kinetic differences between human and Aspergillus fumigatus D-glucosamine-6-phosphate N-acetyltransferase. 2008
Cross-link formation of the cysteine 228-tyrosine 272 catalytic cofactor of galactose oxidase does not require dioxygen. 2008
Structural and functional characterization of a putative polysaccharide deacetylase of the human parasite Encephalitozoon cuniculi. 2009
Molecular mechanisms of yeast cell wall glucan remodeling. 2009
Molecular mechanism of elongation factor 1A inhibition by a Legionella pneumophila glycosyltransferase. 2010

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