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Ser and Thr Acceptor Preferences of the GalNAc-Ts Vary Among Isoenzymes to Modulate Mucin Type O-Glycosylation 2020
A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor 2020
Synthesis, Conformational Analysis and in vivo Assays of an Anti-cancer Vaccine that features an Unnatural Antigen based on a sp2-Iminosugar Fragment 2020
Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3 2020
A Bump-and-Hole Approach to Dissect Regulation of Protein O-Glycosylation. 2020
Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase 2020
Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage. 2019
Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases. 2019
Anti-tumoral potential of a human granulysin-based, CEA-targeted cytolytic immunotoxin 2019
Polypeptide GalNAc-Ts: from redundancy to specificity. 2019
Evidence for substrate-assisted catalysis in N-acetylphosphoglucosamine mutase. 2018
Site-Specific O-Glycosylation of Low-Density Lipoprotein Related Receptors Enhance Ligand Interactions. 2018
Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions. 2018
A perspective on structural and mechanistic aspects of protein O-fucosylation. 2018
Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4 2018
Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts. 2018
Structural basis for arginine glycosylation of host substrates by bacterial effector proteins. 2018
Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition. 2018
Inhibitors against Fungal Cell Wall-remodelling Enzymes. ChemMedchem, 2018
Choline Kinase Inhibition and Docking Studies of a Series of 6-(benzylthio)-9H-purin-9-yl-pyridinium derivatives. 2017